TB-500 is a synthetic peptide associated with thymosin beta-4 research and is studied in experimental models involving cellular migration, actin regulation, angiogenesis, and tissue remodeling pathways.
Tissue Remodeling Research
Investigated in laboratory models examining cellular processes involved in tissue remodeling.
Cellular Migration
Studied for its relationship with cellular migration and movement within experimental systems.
Actin Regulation
Researched for its interaction with actin-related pathways involved in cellular structure and function.
Angiogenesis Research
Used in experimental research exploring mechanisms associated with blood vessel formation and cellular signaling.
TB-500 corresponds to a fragment of thymosin β4, a small protein whose best-documented function is binding actin — sequestering monomeric actin and taking part in how cells build and dismantle their internal scaffolding.
The critical point, and the one most often lost: the fragment is not the protein. Thymosin β4 is the molecule with the characterised actin-binding role. A fragment of it may or may not carry that property, and conflating the two makes the literature much more confusing than it needs to be.
Handling and reconstitution
Standard lyophilised peptide handling applies. Keep the sealed vial cold and dark until it is used. Reconstitute by running bacteriostatic water slowly down the inside wall of the vial rather than firing it onto the powder cake, and let it dissolve without shaking — swirl gently if it needs help.
The concentration you end up with is set by how much water you add, not by the vial size. Our reconstitution calculator turns vial mass and water volume into a concentration and a syringe reading.
Storage
Sealed and lyophilised: refrigerated, protected from light. In solution: refrigerated, and treat time at room temperature as a cost. Avoid repeated freeze-thaw once reconstituted.
What ships, and what is on the certificate
The vial ships sealed as it was filled. Every compound in the catalogue is tested by an outside laboratory — Vanguard Laboratory in Olympia, Washington — and the certificate is published in full rather than summarised.
The certificate reports chromatographic purity by HPLC with the chromatogram visible, the measured quantity in milligrams, and an endotoxin result by LAL. Measured quantity usually reads slightly above the label, which is normal: fills are targeted high so every vial meets its stated content.
Frequently asked questions
Is TB-500 the same thing as thymosin beta-4?
No. It corresponds to a fragment of it. Thymosin beta-4 is the protein with the documented actin-binding role; a fragment does not automatically inherit that.
What does thymosin beta-4 do?
Its best-characterised role is binding monomeric actin, taking part in how cells assemble and disassemble their internal scaffolding.
How should it be reconstituted?
Add bacteriostatic water slowly down the inside wall of the vial, then let it dissolve without shaking. The reconstitution calculator will convert vial mass and water volume into a concentration and a syringe reading.
Does it come with a certificate of analysis?
Yes. Every compound is tested by an independent laboratory and the full certificate, chromatogram included, is published on the site rather than summarised.
Is this a medicine?
No. It is sold for in-vitro laboratory research use only. It is not a drug, supplement or cosmetic, and is not for human or veterinary use.
Reviews
There are no reviews yet.